Here's a tip: if tackling a large canvas intimidates you test out your design on a small piece of canvas or do a quick sketch of what you want on a piece of paper.
Here are some of my gal pals making waves in the art-o-sphere check them out:
Philece. R - ThatArtista
(photos: Lonny Magazine, Matchbook Magazine, Philece. R, Claire Almon, Jenifer Gheduzzi, Allison Torneros)